Contact

• workRoom BB74 Block B
  Malaysia Campus
  Jalan Broga
  43500 Semenyih
  Selangor Darul Ehsan
  Malaysia
• Kok.ZhiYuan@nottingham.edu.my

Biography

Zhi Yuan obtained his Masters of Pharmacy (MPharm) and Ph.D. degree in the field of medicinal chemistry at the 188体育网址_188体育在线-【唯一授权网站】@ of Nottingham (UoN), the latter of which funded by the prestigious UoN Vice Chancellor's Scholarship for 188体育网址_188体育在线-【唯一授权网站】@ Excellence. After spending just under 3 years as a medicinal/organic chemist collectively at Sygnature Discovery in Nottingham and Nanyang Technological 188体育网址_188体育在线-【唯一授权网站】@ in Singapore, Zhi Yuan rejoins the 188体育网址_188体育在线-【唯一授权网站】@ of Nottingham Malaysia as an assistant professor. Apart from being a keen chemist, Zhi Yuan has a strong interest in G-protein coupled receptors (GPCRs) and novel antimicrobial discovery, as well as exploring the development and wider use of fluorescent compounds for the understanding of biological processes and drug development purposes.

Expertise Summary

- Medicinal Chemistry

- Synthetic Organic Chemistry

Teaching Summary

Subject areas of competence: Medicinal chemistry, organic chemistry, molecular pharmacology

Module convener/contributor for the modules:

Bachelor of Pharmacy: PHAR1038 (Bacterial and Fungal Infections), PHAR2040 (Cardiovascular)

Master of Pharmacy: PHAR1034 (Human Life Cycle), PHAR2044 (Infections 1), PHAR2045 (Infections 2), PHAR2051 (Cardiovascular)

Pharmaceutical and Health Sciences: PHAR1026 (Pharmaceutical and Biological Chemistry), PHAR2010 (Pharmaceutical Analysis and Spectroscopy), PHAR3014 (Medicinal Chemistry and Drug Design)

Recent Publications

• ZHANG, BO, LU, DERONG, WANG, DENNIS BAO RONG, KOK, ZHI YUAN, CHAN-PARK, MARY B. and DUAN, HONGWEI, 2024. Enzyme-Responsive Polyion Complex Nanoparticles of Cationic Antimicrobials for Activatable Antibacterial Therapy Advanced Functional Materials. n/a(n/a), 2407869. IF (2022): 19.0; T10
• MELVIN YONG, ZHI Y. KOK, CHONG H. KOH, WENBIN ZHONG, JUSTIN TY. NG, YUGUANG MU, MARY B. CHAN-PARK and YUNN-HWEN GAN, 2023. Membrane Potential-Dependent Uptake of Cationic Oligoimidazolium Mediates Bacterial DNA Damage and Death Antimicrobial Agents and Chemotherapy. 0(0), e00355-23. IF (2022): 4.9; Q1
• KOK, ZHI YUAN, STODDART, LEIGH A., MISTRY, SARAH J., MOCKING, TAMARA A. M., VISCHER, HENRY F., LEURS, ROB, HILL, STEPHEN J., MISTRY, SHAILESH N. and KELLAM, BARRIE, 2022. Optimization of Peptide Linker-Based Fluorescent Ligands for the Histamine H1 Receptor Journal of Medicinal Chemistry. 65(12), 8258-8288. IF (2022): 7.3; T10
• KOK, ZHI YUAN, STODDART, LEIGH A., MISTRY, SARAH J., MISTRY, SHAILESH N. and KELLAM, BARRIE, 2019. Optimization of Peptide Linker-Based Fluorescent Ligands for the Histamine H1 Receptor In: 27th Annual GP2A Medicinal Chemistry Conference, August 2019, Nottingham, United Kingdom.

• View all publications

• ZHANG, BO, LU, DERONG, WANG, DENNIS BAO RONG, KOK, ZHI YUAN, CHAN-PARK, MARY B. and DUAN, HONGWEI, 2024. Enzyme-Responsive Polyion Complex Nanoparticles of Cationic Antimicrobials for Activatable Antibacterial Therapy Advanced Functional Materials. n/a(n/a), 2407869. IF (2022): 19.0; T10
• MELVIN YONG, ZHI Y. KOK, CHONG H. KOH, WENBIN ZHONG, JUSTIN TY. NG, YUGUANG MU, MARY B. CHAN-PARK and YUNN-HWEN GAN, 2023. Membrane Potential-Dependent Uptake of Cationic Oligoimidazolium Mediates Bacterial DNA Damage and Death Antimicrobial Agents and Chemotherapy. 0(0), e00355-23. IF (2022): 4.9; Q1
• KOK, ZHI YUAN, STODDART, LEIGH A., MISTRY, SARAH J., MOCKING, TAMARA A. M., VISCHER, HENRY F., LEURS, ROB, HILL, STEPHEN J., MISTRY, SHAILESH N. and KELLAM, BARRIE, 2022. Optimization of Peptide Linker-Based Fluorescent Ligands for the Histamine H1 Receptor Journal of Medicinal Chemistry. 65(12), 8258-8288. IF (2022): 7.3; T10
• KOK, ZHI YUAN, STODDART, LEIGH A., MISTRY, SARAH J., MISTRY, SHAILESH N. and KELLAM, BARRIE, 2019. Optimization of Peptide Linker-Based Fluorescent Ligands for the Histamine H1 Receptor In: 27th Annual GP2A Medicinal Chemistry Conference, August 2019, Nottingham, United Kingdom.
• KOK, ZHI YUAN, STODDART, LEIGH A., MISTRY, SARAH J., MISTRY, SHAILESH N. and KELLAM, BARRIE, 2019. Optimization of Peptide Linker-Based Fluorescent Ligands for the Histamine H1 Receptor In: G Protein-Coupled Receptors: New Techniques, Tools and Concepts, November 2019, Copenhagen, Denmark.
• HOSSAN, MD SHAHADAT, AHMED, NAJNEEN, LEE, JONG BONG, KOK, ZHI YUAN, GERSHKOVICH, PAVEL, COLLINS, HILARY M., RAHMATULLAH, MOHAMMED, WIART, CHRISTOPHE and BRADSHAW, TRACEY D., 2018. In vitro anticancer effect and biological evaluation of Trichosanthes bracteata (Lam.) Voigt. In: 18th International Congress of International Society for Ethnopharmacology and 5th International Congress of the Society for Ethnopharmacology, India, Jan 2018, Dhaka, Bangladesh.
• KOK, ZHI YUAN, MISTRY, SARAH J., HILL, STEPHEN J., MISTRY, SHAILESH N. and KELLAM, BARRIE, 2018. Optimization of Peptide Linker-Based Fluorescent Ligands for the Histamine H1 Receptor In: 7th RSC/SCI Symposium on GPCRs in Medicinal Chemistry, September 2018, Verona, Italy.